Quick collider question

Say I have a script which spawns a (Gameobject) collider at position "X" in 5 seconds. The collider is 50 squared.
If there were colliders within that 50 meters, like, say, enemies, would they still collide?
So basically I'm asking if the inside of colliders allow for collisions, or is it just the borders of them?

 

A collider that is fully inside another collider will still trigger the collision. When triggers are involved, this collision may be a frame late.